Taking Rabeprazole 20mg since 2010 for longstanding Gord/gastritis. Biopsy 2013 moderate PPI effect on acid secreting tubules. Intestinal metaplasia?

Long Use of a PPI. Proton Pump Inhibitors (PPIs) are increasing considered a risk issue in long-term use. While it is difficult to answer your question specifically without further information, consider that for GERD and Gastritis, non-drug interventions such as a wedge pillow and changes in your diet can be an alternative to long-term PPI usage and exposure to potential side effects.