4 doctors weighed in:

Why hydroxychloroquine is effective in treating systemic lupus erythematosus?

4 doctors weighed in
Dr. Thomas Namey
Internal Medicine - Rheumatology
3 doctors agree

In brief: It is magic?

1the use of anti-malarials in autoimmune diseases was accidentally discovered in treating wwii vets for malaria.
Those with RA improved. Chloroquine and ho-q were tested in sle, with very positive results. In the early 80's canadian researchers definitively showed fewer sle flares with ho-q. It is considered the rx of first choice for :sle. We now understand more of the mechanisms, but not all.

In brief: It is magic?

1the use of anti-malarials in autoimmune diseases was accidentally discovered in treating wwii vets for malaria.
Those with RA improved. Chloroquine and ho-q were tested in sle, with very positive results. In the early 80's canadian researchers definitively showed fewer sle flares with ho-q. It is considered the rx of first choice for :sle. We now understand more of the mechanisms, but not all.
Dr. Thomas Namey
Dr. Thomas Namey
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