What happens if I'm taking klonopin and zoloft, (sertraline) can I have a least 1 beer?

Not Recommended. "at least 1 beer??", how about, at most 1 beer. Klonopin (clonazepam) which is a benzodiazepine, when mixed with alcohol, can produce respiratory depression, and subsequent death. With one beer, and a low dose of Klonopin (clonazepam), it may be a low risk, but it is certainly not suggested nor recommended.

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What to do if I am taking 1mg of klonopin and one 25mg of zoloft, (sertraline) and one 50mg of inderol for blood pressure, is it ok to have 1 12oz beer?

NO ALCOHOL! You cannot combine klonopin and alcohol. Klonopin stays in your system for more than a day after taking it as well. The combination can have an unpredictable / multiplying effect on sedation, respiratory depression, and intoxication. Alcohol is not worth the risk. Alcohol can also temparily lower your blood pressure which may not be good to do with Inderal (propranolol) on board. Read more...