4 doctors weighed in:
Is low HDL as much a cardiovascular risk as high ldl? Does HDL numbers really matter if LDL is under control? Lots of conflicting info out there.
4 doctors weighed in

Dr. Paul Diamond
Family Medicine
1 doctor agrees
In brief: Agreed
Yes, lots of conflicting material.
Right now, it seems that high ldl, especially LDL particle number is high can be a culprit - get a more sophisticated blood test than a "calculated ldl." you can have a normal LDL at 99, but the particle number may be 1800 which is high. Hdl should be over 40, but many people genetically have them in the 20's.

In brief: Agreed
Yes, lots of conflicting material.
Right now, it seems that high ldl, especially LDL particle number is high can be a culprit - get a more sophisticated blood test than a "calculated ldl." you can have a normal LDL at 99, but the particle number may be 1800 which is high. Hdl should be over 40, but many people genetically have them in the 20's.
Dr. Paul Diamond
Dr. Paul Diamond
Thank
Dr. Edward Hoffer
Internal Medicine - Cardiology
1 doctor agrees
In brief: Generally, yes
At any given level of total and LDL cholesterol, the higher the HDL the lower the cardiac risk and vice-versa.
The reason doctors tend to focus on lowering LDL is that there are to date no proven results from raising HDL with drugs, the one exception being niacin, notoriously hard to take in meaningful amounts. Low HDL may be a marker of risk rather than a target for treatment.

In brief: Generally, yes
At any given level of total and LDL cholesterol, the higher the HDL the lower the cardiac risk and vice-versa.
The reason doctors tend to focus on lowering LDL is that there are to date no proven results from raising HDL with drugs, the one exception being niacin, notoriously hard to take in meaningful amounts. Low HDL may be a marker of risk rather than a target for treatment.
Dr. Edward Hoffer
Dr. Edward Hoffer
Thank
Dr. Milton Alvis Jr
Preventive Medicine
In brief: Yes, though Debated
Dr. Cromwell's answer is the most informed & accurate.
The correct issues, from basic & science clinical research for >60 years has always been the fat carrying particles (not one particular fat they carry, such a cholesterol) & traffic patterns of where the fat going vs. Being removed. Cells, if overloaded with intracellular fat become sick & die. Ldl-p deliver, large hdl-p remove fat molecules.

In brief: Yes, though Debated
Dr. Cromwell's answer is the most informed & accurate.
The correct issues, from basic & science clinical research for >60 years has always been the fat carrying particles (not one particular fat they carry, such a cholesterol) & traffic patterns of where the fat going vs. Being removed. Cells, if overloaded with intracellular fat become sick & die. Ldl-p deliver, large hdl-p remove fat molecules.
Dr. Milton Alvis Jr
Dr. Milton Alvis Jr
Thank
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