What kind of pain medicine has the least side effects next to acetaminophen, ibuprofen and nsaids?

Premise is wrong. Aspirin and nsaids can cause GI and renal issues. Tylenol (acetaminophen) causes hepatic problems. Neither are "safe" unless you know what the patient's comorbidities are. All meds have "side effects", the issue is, whih ones are you best able to tolerate?

Related Questions

What pain medicine has the least side effects? Worried about recalls of acetaminophen, ibuprofen and nsaids?

Acetaminophen. Other than for the cyanide scare of 1982 (which has been effectively prevented since by changes in packaging), Acetaminophen has not been recalled and tends to have fewer side effects than nsaids. It is effective for lowering fever and is good pain reliever for mild pain. It doesn't cause bleeding and doesn't upset the stomach at prescribed doses. Read more...