Will noroxin (norfloxacin) antibiotics cause harm if used in pregnancy?

Maybe. Noroxin and its cousins (fluoroquinolone antibiotics such as Cipro (ciprofloxacin) and levaquin) probably do not cause birth defects. However, there is some concern that these antibiotics might damage a baby's joints, but this is based on animal studies only. For now, we typically avoid these antibiotics unless there isn't a good alternative.