3 doctors weighed in:

My husband is taking mestinon, (pyridostigmine) methotrexate, and prednisone for myasthenia gravis. Are all 3 needed?

3 doctors weighed in
Dr. Loki Skylizard
Surgery - Thoracic
1 doctor agrees

In brief: Quite possibly

About 1/3 can see spontaneous remission, 1/3 stabilize on chronic medications, and 1/3 have progressive difficulties.
In appropriate candidates, minimally invasive thoracic surgery to remove thymus (thymectomy) can possibly cure or stabilize disease or decrease amount and/or types of meds. This link may help: http://goo.Gl/3xxmd.

In brief: Quite possibly

About 1/3 can see spontaneous remission, 1/3 stabilize on chronic medications, and 1/3 have progressive difficulties.
In appropriate candidates, minimally invasive thoracic surgery to remove thymus (thymectomy) can possibly cure or stabilize disease or decrease amount and/or types of meds. This link may help: http://goo.Gl/3xxmd.
Dr. Loki Skylizard
Dr. Loki Skylizard
Thank
Dr. Jay Rosenfeld
Physical & Rehabilitation Medicine

In brief: See below

Myesthenia gravis is an autoimmune disease.
That means that the body produces antibodies that attack normal tissue. In the case of mg, the antibodies attack the receptor that chemically links the nerves to the muscles. The Mestinon (pyridostigmine) improves nerve transmission so the muscles work better. The Methotrexate and Prednisone suppress the production of antibodies that attack the receptors.

In brief: See below

Myesthenia gravis is an autoimmune disease.
That means that the body produces antibodies that attack normal tissue. In the case of mg, the antibodies attack the receptor that chemically links the nerves to the muscles. The Mestinon (pyridostigmine) improves nerve transmission so the muscles work better. The Methotrexate and Prednisone suppress the production of antibodies that attack the receptors.
Dr. Jay Rosenfeld
Dr. Jay Rosenfeld
Thank
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