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Can cancer cells become resistant to the damaging effects of melphalan?
1 doctor weighed in

Dr. Andrew Turrisi
Radiation Oncology
In brief: L-PAM or
Melphalan is l phenyalanine mustard, one of the oldest alkylating agents.
Yes, resistance occurs. Also dns damage can be associated with leukemia. These agents are uncommonly used today, used to be the agent in breast cancer, now never used, and may still be used in blood/lymphatic malignancies.

In brief: L-PAM or
Melphalan is l phenyalanine mustard, one of the oldest alkylating agents.
Yes, resistance occurs. Also dns damage can be associated with leukemia. These agents are uncommonly used today, used to be the agent in breast cancer, now never used, and may still be used in blood/lymphatic malignancies.
Dr. Andrew Turrisi
Dr. Andrew Turrisi
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