7 doctors weighed in:

Can you have renal tubular acidosis with an elevated serum anion gap?

7 doctors weighed in
Dr. David Carl Houghton
Internal Medicine & Pediatrics
5 doctors agree

In brief: Yes

RTA doesn't cause elevated anion gap, but other disorders that do can be present along with RTA.
For example, advanced kidney failure can cause anion gap, and also cause RTA. Usually simple math will show that the anion gap doesn't completely account for the degree of acidosis, and urine tests can demonstrate presence of RTA.

In brief: Yes

RTA doesn't cause elevated anion gap, but other disorders that do can be present along with RTA.
For example, advanced kidney failure can cause anion gap, and also cause RTA. Usually simple math will show that the anion gap doesn't completely account for the degree of acidosis, and urine tests can demonstrate presence of RTA.
Dr. David Carl Houghton
Dr. David Carl Houghton
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Dr. Patrick Kohlitz
Internal Medicine

In brief: Possible

The textbook answer is no.
Generally, RTA presents with a normal anion gap. However, if concurrent conditions of dyselectrolytemias exist the gap may be elevated.

In brief: Possible

The textbook answer is no.
Generally, RTA presents with a normal anion gap. However, if concurrent conditions of dyselectrolytemias exist the gap may be elevated.
Dr. Patrick Kohlitz
Dr. Patrick Kohlitz
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