4 doctors weighed in:

Can one's body develop a resistance to Benadryl (diphenhydramine) if one takes it on a daily basis? Will the medicine eventually lose it's effectiveness as time passes?

4 doctors weighed in
Dr. Robert Greer
Family Medicine
3 doctors agree

In brief: Yes

All antihistamines can lose effectiveness.
Most are over the counter now and i'd recommend switching to another family like allegra, claritin, (loratadine) or tavist.

In brief: Yes

All antihistamines can lose effectiveness.
Most are over the counter now and i'd recommend switching to another family like allegra, claritin, (loratadine) or tavist.
Dr. Robert Greer
Dr. Robert Greer
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