Not same. But they are similar (non steroidal anti-inflammatory drugs). Aleve (aka naprosyn/naproxen) is taken twice a day whereas ibuprofen (aka Motrin, Advil) is a med that can be taken every 6 to 8 hours (this 3 or 4 times a day). Both drugs work by reducing the inflammatory response by the body. You should use one or the other, but not both at the same time to reduce risk of GI upset and kidney stress .