Ladies have anyone of you taken a hormone drug call estradiol if so did you have any side effect.?

YES. I am not a lady; however, I am a gentleman. Estradiol is a powerful hormonish type, and it has a nasty rep. Cancer, fetal malformities for starters. Yes & yes again; there are indications for its use;however after all ''the ladies'', how about the physician that prescribed it. I agree, it was obvious.