Negative side-effects with compazine (prochlorperazine)?

Compazine (prochlorperazine) Side effects of Compazine (prochlorperazine) can be serious and are related to the compound itself, which is a mild anti-psychotic drug with structure similar to other older antiphyschotics. Serious effects can involve spastic movement, temperature increase and muscle breakdown with high fever that is life threatening in rare cases. More common is spastic movements called extra-pyramidal effects, disjointed mvmt.