Yes, absolutely. 5fu (fluorouracil) based chemotherapy is the standard chemotherapy in colon cancer. Combination of 5-FU and oxaliplatin is widely used and a standard regiment of chemotherapy in colorectal cancer. A big randoomized clinical trial in colon cancer (mosaic study) has demonstrated the overall survival benefit of using combination of 5fu (fluorouracil)/oxaliplatin in stage iii colon cancer and limited case of stage ii disease.
Depends on stage etc. While that combination is not the standard for adjuvant chemotherapy (given after the primary cancer is removed), it has been used in clinical trials for adjuvant as well as neoadjuvant treatment (combination therapy given as first line, before removal of the primary tumor). Cancer resut is good but complications have been higher.
Eloxatin (oxaliplatin) Eloxatin (oxaliplatin) is beneficial in the treatment of colon & rectal cancers.
Immunotherapy. If primary lesion present it is essential to be resected. If lesion already removed and oxaliplatin advocated as part of chemo, other option are Xelodac given orally or avastin (bevacizumab) as a monoclonal antibody. In addition there is Erbitux, an epidermal growth factor 1 inhibitor, radiation to the site of potential recurrence and newer monoclonals in FDA trials targeting tumor protein.
My grandfather, 80 y/o stage 4 colon cancer has been put on: levoronin, eloxatin, avastin, (bevacizumab) 5-fo. Is this appropriate for his first round of chemo?
Discuss with doctor. You should discuss these findings with your doctor. You could reopen the cervix to drain the fluid, but, given the paucity of symptoms, that may not be necessary.
Yes. Becaused it's based on the guidelines for stage 4 colon cancer.
A pre- Cancerous polyp can convert to a cancer in 4-5 years which is why people with a history of multiple polyps should get colonoscopy more often than every 10 years.
Yes. A majority of colorectal cancers, if they recur, recur within 3-5 years, but it is possible to recur later as well. The other possibility is development of new cancers or polyps, which is why surveillance/screening colonoscopy may be warranted. Ask your doctor/surgeon for more information.
Yes it can, rarely. Late relapses (after 5 years) are uncommon but not unheard of. So it is not a total surprise.
Yes. Yes. Any cancer can come back at any time. Cancer doesn't listen to doctors or textbooks very well. However, for most cancers, including colon cancer, being 5 years out ned (no evidence of disease) is a practical definition of cure. Likelihood of recurrence is low.