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What is the procedure for withdrawal off loxapine?
2 doctors weighed in

Dr. Seth Kunen
Clinical Psychology
1 doctor agrees
In brief: Slow over 6-8 weeks
Slow tapering of oral formulation over 6–8 weeks, especially when simultaneously beginning a new replacement antipsychotic.
Rapid oral discontinuation may lead to rebound psychosis and worsening of symptoms. If antiparkinson agents are being used, they should be continued for a few weeks after Loxapine is discontinued. [see stahl].

In brief: Slow over 6-8 weeks
Slow tapering of oral formulation over 6–8 weeks, especially when simultaneously beginning a new replacement antipsychotic.
Rapid oral discontinuation may lead to rebound psychosis and worsening of symptoms. If antiparkinson agents are being used, they should be continued for a few weeks after Loxapine is discontinued. [see stahl].
Dr. Seth Kunen
Dr. Seth Kunen
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