Yes. I am a male physician, so I have not tried it for my personal use, but I have treated hundereds of women succesfully with flutamide.
Yes. Flutamide is a type of anti-androgen that blocks the affect of male hormones on the tissues themselves. It is generally not considered a first line drug of choice, (spironolactone/aldactone is), is a bit more expensive and really requires an occasional follow-up of liver blood tests. Otherwise, it can work quite well, especially with the combination of a hormonal pill/patch or vaginal ring.