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What is disulfiram (antabuse) and what is it used for?

2 doctors weighed in
Dr. Stuart Wasser
Addiction Medicine
1 doctor agrees

In brief: See below

Disulfiram is approved as a treatment for alcohol dependence.
It works by interfering with the breakdown of alcohol leading to an accumulation of acetaldehyde which causes nausea and flushing. It also seems to slow metabolism of Dopamine which has led to its having a small role in Cocaine dependence.

In brief: See below

Disulfiram is approved as a treatment for alcohol dependence.
It works by interfering with the breakdown of alcohol leading to an accumulation of acetaldehyde which causes nausea and flushing. It also seems to slow metabolism of Dopamine which has led to its having a small role in Cocaine dependence.
Dr. Stuart Wasser
Dr. Stuart Wasser
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