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Why is clofibrate contraindicated in patients with renal failure?
2 doctors weighed in

Dr. Fred McCurdy
Pediatrics - Nephrology & Dialysis
1 doctor agrees
In brief: Clofibrate
Clofibrate is a lipd lowering drug that is metabollized in the liver. Those metabolites are excreted in the kidney.
When renal failure/insufficiency happens, the drug itself as well as its metabolites build up in the blood. High concentrations of these metabolites can lead to serious side effects including death. So, don't take Clofibrate if you have renal disease.

In brief: Clofibrate
Clofibrate is a lipd lowering drug that is metabollized in the liver. Those metabolites are excreted in the kidney.
When renal failure/insufficiency happens, the drug itself as well as its metabolites build up in the blood. High concentrations of these metabolites can lead to serious side effects including death. So, don't take Clofibrate if you have renal disease.
Dr. Fred McCurdy
Dr. Fred McCurdy
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