9 doctors weighed in:

I tested positive ANA and anti dsdna, later testing neg. I have past diagnosis that may apply to lupus but do not do well articuliatng at dr. Help?

9 doctors weighed in
Dr. Pierre Moeser
Internal Medicine - Rheumatology
7 doctors agree

In brief: Tests and lupus

The question is why is the doctor running the tests? If your symptoms and physical signs are a strong indication of possible lupus, positive dsdna helps confirm a diagnosis of lupus.
If the tests are run for "screening", they are worthless tests. No diagnosis of lupus or connective tissue disease can be made on antibody studies alone.

In brief: Tests and lupus

The question is why is the doctor running the tests? If your symptoms and physical signs are a strong indication of possible lupus, positive dsdna helps confirm a diagnosis of lupus.
If the tests are run for "screening", they are worthless tests. No diagnosis of lupus or connective tissue disease can be made on antibody studies alone.
Dr. Pierre Moeser
Dr. Pierre Moeser
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1 comment
Dr. Thomas Namey
Treatment with antimalarials can revert the dsDNA test to normal.
Dr. Chad Boomershine
Internal Medicine - Rheumatology
1 doctor agrees

In brief: +ANA does not=lupus

95% of people with a positive ANA test do not have lupus.
Lupus can only be diagnosed by a rheumatologist. Lab tests are not sufficient to diagnose lupus. See a rheumatologist.

In brief: +ANA does not=lupus

95% of people with a positive ANA test do not have lupus.
Lupus can only be diagnosed by a rheumatologist. Lab tests are not sufficient to diagnose lupus. See a rheumatologist.
Dr. Chad Boomershine
Dr. Chad Boomershine
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