10 doctors weighed in:
I'm considering taking elavil or tofranil (imipramine) for depression. Which is best?
10 doctors weighed in

Dr. Steven Reidbord
Psychiatry
4 doctors agree
In brief: They're very similar
Elavil (amitriptyline) (amitripyline) and tofranil (imipramine) are both tricyclic antidepressants, an older category.
While they are effective against depression, both can cause antihistamine-like effects e.g., sedation, dry mouth, dry eyes, constipation, and temporary trouble focusing vision. Elavil (amitriptyline) does this a little more, so tofranil may be better unless elavil's extra sedation helps.

In brief: They're very similar
Elavil (amitriptyline) (amitripyline) and tofranil (imipramine) are both tricyclic antidepressants, an older category.
While they are effective against depression, both can cause antihistamine-like effects e.g., sedation, dry mouth, dry eyes, constipation, and temporary trouble focusing vision. Elavil (amitriptyline) does this a little more, so tofranil may be better unless elavil's extra sedation helps.
Dr. Steven Reidbord
Dr. Steven Reidbord
Thank
Dr. Douglas Bey
Psychiatry
3 doctors agree
In brief: Both r good
These r old tricyclics antidepressants that r as effective as the newer ones but have more side effects--dry mouth constipation hot flashes etc Elavil (amitriptyline) is more sedating of the two the both can cause cardiac changes in high doses--some people do well on one and some on the other--if someone in your family is doing well on one pick it.

In brief: Both r good
These r old tricyclics antidepressants that r as effective as the newer ones but have more side effects--dry mouth constipation hot flashes etc Elavil (amitriptyline) is more sedating of the two the both can cause cardiac changes in high doses--some people do well on one and some on the other--if someone in your family is doing well on one pick it.
Dr. Douglas Bey
Dr. Douglas Bey
Thank
1 comment
Dr. Alan Ali
I recommend talking to your doctor before making any changes.
Dr. Alan Ali
Psychiatry
2 doctors agree
In brief: Depression
Your doctor can evaluate & provide the best advice.

In brief: Depression
Your doctor can evaluate & provide the best advice.
Dr. Alan Ali
Dr. Alan Ali
Thank
Dr. Susan Uhrich
Psychiatry
2 doctors agree
In brief: The best
Medication of any kind is the one that works for you with the fewest side effects.

In brief: The best
Medication of any kind is the one that works for you with the fewest side effects.
Dr. Susan Uhrich
Dr. Susan Uhrich
Thank
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