Do fertility drugs increase your risk of developing ovarian cancer?

Minimal. If there is a risk, is with Clomid (clomiphene) after 12 months of use and the risk is minimal. The greatest risk is infertility itself and not the medications. In the grand majority of patients there is no reason to use Clomid (clomiphene) for 12 months. The treatment is usually changed if the patient has not conceived after 4-6 cycles.
Not conclusively. The largest, most rigorously designed trial ever to address the question shows “no convincing association” between fertility drug use and ovarian cancer. The medical records of 54, 362 infertile women treated at fertility clinics in denmark between 1963 and 1998 were reviewed and no conclusive relationship was made between ovarian cancer and pro fertility drugs.

Related Questions

Heard again that fertility drugs are linked to ovarian cancer. Thought that was not true. Now not sure what to believe. Do I need ultrasounds yearly?

Infertility Yes Rx N. Infertility and having no children are independent risk factors for ovarian cancer. Some injectable super-ovulation drugs had some initial concern for increasing cancer risk but most believe that any increase in risk is minimal. No specific screening is recommended for ovarian cancer. Ca-125 testing and ultrasound have not been effective at determining who will develop ovarian cancer. Read more...
Sort of. I agree with the previous answer. Here's the way to see it conceptually..The more stimulation and turnover of any cell line, like those in the ovary, the more there is a risk of an error or mistake in the new line of cells, so the short answer is yes. But, the actual increased risk is minimal. Then monitor with sonos, annual pelvic exams, and both ca125 and he4 tests. Plus, eat right. Read more...

Heard again that fertility drugs are linked to ovarian cancer. Thought that was not true. Now not sure what to believe. Do I need ultrasounds yearly?

No. Many years ago, there was a poorly done study linking women who took a certain fertility drug for more than 1 year to ovarian cancer. Since that time no link has been found. Even in that past study, women who had a least 1 child had no increased risk. We know that woman who never give birth have a higher risk of ovarian cancer. There is no reason to believe fertility drugs increase this risk! Read more...
A qualified no. A very recent study did show a possible association between fertility medication and a specific type of low-risk ovarian cancer. It is unclear if this is a real phenomenon, and unclear if the risk is merely associated with or actually caused by fertility meds. And at worst, it would be a very small effect. But yearly ultrasounds are not a good screening test for ovarian cancer! talk to your doctor. Read more...
No ultrasounds. Anything that stimulates the ovaries can theoretically increase risk for ovarian cancer, whether fertility drugs or the constant stimulation of uninterrupted monthly cycles in women who never get pregnant. However, the risk is low. There is no good screening test for ovarian cancer, so just pay attention to your body and let your doctor know of any abdominal discomfort. And try not to worry! Read more...

Does circulating IGF-1 increase as a result of ovarian cancer (in other words, does the cancer itself cause the increase in IGF-1)?

Yes, it can. I'm not an expert but I have seen some literature to suggest that IGF1 may be one of the markers released by certain ovarian cancer cells, as well as several IGF receptor proteins. It looks as if this might increase the virulence of the cancer. If you are concerned about yourself, ask the doctor who tested you for more guidance. Good luck. Read more...

Does the use of talc (talcum powder) as a feminine powder increases the risk of ovarian cancer?

Sometimes. The world health organization classifies talc that contains asbestos as a carcinogen and talc without asbestos as not yet classifiable. Several studies have shown an increase in ovarian cancer with talc use as high as 300% after daily use for 25 years. The problem is that some talc contains asbestos and some does not and the label does not have to disclose that it is present. Best to avoid it. Read more...
Maybe. Great question. There is some data that talc crystals have been found on surface ovarian cancers increasing the suspicion that talc is involved in ovarian cancer. There is also data that getting a tubal ligation, which can prevent talc crystals from getting to ovary, can decrease the risk of ovarian cancer. However, the exact answer is not known. Best idea is to avoid talc in the vagina or vulva. Read more...

Could a cyst be a sign of ovarian cancer if you have premature ovarian failure? I have awful pain, increased urination and prolonged heavy bleeding.

Complicated. If you have premature ovarian failure, you should not be bleeding. Have you had an ultrasound to confirm that you have a cyst? Ovarian cancer is relatively uncommon in your 30's, but not impossible. See your gyn to have all of these issues addressed. Good luck! Read more...
Ovarian cancer. It sounds as if you have other things going on also. You should not be bleeding if you have ovarian failure. You need to have an endometrial biopsy as well as have your ovaries evaluated. Read more...