KGF and hair growth
keratinocyte growth factor-2 (kgf-2) is found in dermal papilla fibroblasts and its receptor, fibroblast growth factor receptor 2 (fgfr2), in the neighboring outer root sheath of keratinocytes.
Administration of recombinant human kgf-2 (rhkgf-2) at 10 ng ml(-1) significantly stimulated human hair-follicle
cell proliferation in organ culture (26-35%). Thus, rhkgf-2 is a promising therapeut.