4 doctors weighed in:

Could anybody get the mthfr-a1298c gene mutation?

4 doctors weighed in
Dr. Su Fairchild
Integrative Medicine
2 doctors agree

In brief: Depends

The MTHFR 1298 mutation is not uncommon, but for any given individual to have the possibility of having it, one or both of their parents must have it.

In brief: Depends

The MTHFR 1298 mutation is not uncommon, but for any given individual to have the possibility of having it, one or both of their parents must have it.
Dr. Su Fairchild
Dr. Su Fairchild
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1 comment
Dr. Rhonda Simons
About 34% of the US population has at least ONE of the 1298 alleles, about 50% have at least ONE of the 677 alleles. 1298's are generally "better" to have as a single allele as they don't lead to elevated homocysteine levels or Uric acid levels-unless you are quite B12 deficient. Still recommend treatment with 15mg of L-Methylfolate, P5P, & methylcobalamin -I use a compounded one covered by insu
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