Can a donut with 380 cals., 21g fat, 15mg cholesterol, 460mg sodium, 46g carbohydrates, 25g sugar raise your blood sugar, cholesterol &blood pressure?

Poor diet. I am a bit surprised. You do not need a physician to tell you that eating a high sugar food would raise your blood sugar. Testing for cholesterol in a non-fasting state makes the test completely invalid. One donut would not cause the disease of hypertension.