Has anyone ever taken levsin (hyoscyamine) or heard for colitis?

Drs. Right. It is an antispasmodic. It offers symptom relief, but does nothing for the GI inflammation. You must be on drugs to control this. Also, its side effects are plentiful, since it anti-cholinergic: can worsen glaucoma, can cause urinary retention, contstipation, and dry mouth.
Used for spasm. Levsin, (hyoscyamine) a form of hyoscamine, is used to treat bowel spasm and also diarrhea related to excessive bowel peristalsis. Caution is advised in the use of the medication for crohn's disease and ulcerative colitis.
No. Levsin (hyoscyamine) is antispasmodic for ibs.