Many possibilities. Unfortunately, conventional therapy has poor success. Alternative therapies are controversial but are worth considering- see www. Cancertutor. Com for an overview. For pancreatic cancer specifically, oncologist nicholas gonzales offers a promising if controversial approach: www. Dr-gonzalez. Com a recent study on homeopathic psorinum had incredible results: www. Hindawi. Com/journals/ecam/2011/724743.
ALA and LDN. Intravenous Alpha lipoic acid and oral low dose Naltrexone have shown some promise in anecdotal reports by dr. Berkson. Intravenous vitamin C has also been suggested to be helpful across a number of cancer types - not sure if pancreatic cancer is included. I believe research at kansas university is ongoing.
Plenty of Rx. But only total removal works. Panc resides in a critical area, if ca invades important vessels removal unlikely. Potential to remove improved with chemo and radiorx. If vessels not freed, stomach and liver secretions need to be bypassed to attain relief.
Details. The latest, best chemotherapy regimen for metastatic disease is folfirinox, a combination regimen, which outperformed gemcitabine alone. Another option is gemcitabine with Paclitaxel or erlotinib. Surgery is the only curative modality, so if its resectable, this should be pursued. Neoadjuvant (pre-op) treatment with chemo and radiation is a great option to ensure patient is likely to benefit.
In addition to gemcitabine, are there any new treatments for advanced pancreatic cancer (in older people)?
Some new chemo. There have been recent presentations at the 2013 asco meeting that have examined combination therapy with Abraxane + gemcitabine that demonstrated that this combination had a statistically improved survival (median=8.5 months) vs gemcitabine alone (median=6.7 months). There is also the chemo combination (folfirinox) which is older and more toxic but has a median survival of 11.1months).
Cyberknife. Aggressive local treatment in addition to chemotherapy has offered good palliation of the symptoms and improvement of local control. Use of cyberknife radiosurgery in elderly with advanced pancreatic cancer patients is usually very well tolerated and improves local control and can offer palliation if patient is symptomatic. Gemzar (gemcitabine) alone or in combination with 5-fu mainstay of systemic therapy.
What is natural/ Chinese therapy? I am not aware of any controlled clinical trials assessing the efficacy of "natural/chinese therapy", therefore I am not able to provide an informed opinion. It is very important to seek traditional care at the earliest since pancreatic cancer has a high mortality rate.
Perhaps. Whenever one of my patients wants to use natural or alternative therapy for a problem. I always ask them to show me exactly what it is they are taking. Some things may help, some things may really do nothing at all, but some things may have bad side effect when combine with other medicines. Your doctor can cross check your alternative medicines with whatever they order.
Not available. Gene therapy for cancers, including pancreatic cancer is not in common use. See this site for more info. Http://www. Mayoclinic. Com/health/gene-therapy/my00105.
Is snus a safe alternative to cigarettes? Snus is being touted as a safe alternative to cigarettes. Studies cite low if non-existent rates of associated lung cancer, with a very mild uptick in pancreatic cancer - the studies were carried out in sweden, a
Snus. Snus is also known as swedish snuff and is a moist powder tobacco product originated from a variant of dry snuff in the early 19th century in sweden, consumed by placing it under the lip for extended periods of time. While it has been touted as an alternative to smoking and traditional "chewing" tobacco, there are concerns regarding health risks associated with its use. Although some say smokeless tobacco poses fewer health risks than cigarettes, they note that it has been linked to various types of cancer and warn against using any tobacco product. There are contradictory studies on the risk for cancer and other health problems. In a study from the karolinska institute in stockholm, sweden, published in the international journal of cancer in 2008 found a statistically significant increase in the incidence of the combined category of oral and pharyngeal cancer among daily users of snus (incidence rate ratio 3.1, 95% confidence interval 1.5-6.6) was found. Overall mortality was also slightly increased (hazard ratio 1.10, 95% confidence interval 1.01-1.21). In an earlier study published in lancet in 2007, snus use was independently associated with increased risk of pancreatic cancer (relative risk for ever-users of snus 2.0; 95% ci 1.2-3.3, compared with never-users of any tobacco), but was unrelated to incidence of oral (0.8, 95% ci 0.4-1.7) and lung cancer (0.8, 0.5-1.3). These differences may also lie in the variations of smokeless tobacco in the marketplace. In a study from 2008, researchers found a large variation in the levels of some toxic compounds and carcinogens analyzed in american and swedish smokeless tobaccos. Based on this and other studies, while smokeless tobaccos provide some protection against lung cancer, the overall health risks or benefits have not been clearly determined and the best advice is to avoid using any tobacco at all.
This. This is a great question. Before I provide any more information, it is important to let you know that because of the decline in sales of tobacco products, nasal snuff may be receiving a lot of press by the tobacco industry in order to improve sales. The second issue is that there has not been an abundance of medical studies on the effects of dry nasal snuff in humans. Dry nasal snuff has been used in europe for hundreds of years. Snuff has different health risks than smoking tobacco or use of wet snuff in the mouth. Dry snuff presents with a lower risk for cardiovascular disease compared to smoking. This could at least in part be due to the fact that snuff does not involve the combustion of carcinogenic materials in tobacco that way that smoking does. Chronic abuse of dry snuff creates changes in the nose. It can lead to atrophy of some of the turbinates and metaplastic changes of some of the tissues in the nose. It can also inhibit mucus clearance by cilia in the nose. There are a paucity of studies regarding cancer and dry snuff. It is being suggested that nasal snuff could be used as substitution therapy for someone who is trying to quit smoking. This is because nicotine is absorbed at a similar rate when using nasal snuff or smoking. One of the problems is that nicotine dependence can occur with any form of tobacco use. The bottom line is that it is not safe to repeatedly take tobacco into the body in any form. Argueably, use of dry snuff has less risk of certain types of health problems than smoking..