What is a dangerously high overdose of amoxicillin? Five times the usual dose? More?

Why do you ask? There is a wide range of dosing for amoxicillin, depending on the infection being treated. In pediatrics, the dose can range from 20 mg/kg to 90 mg/kg. If you think you took too much, call the poison help line at 1-800-222-1222.