Can you take prevacid and relafen (nabumetone) at the same time?

Yes. You need to be monitored for the side effects of Relafen and other nsaids. Prevacid can help decrease the risk of GI bleeding. It is a proton pump inhibitor. Vimovo (esomeprazole and naproxen) even has a proton pump inhibitor in the same pill with the Naproxen and decrease gastric ulcers. The proton pump inhibitors increase the protection from the NSAID induced GI ulcerations and bleeding.