What do you advise if I'm using glucovance, (glyburide and metformin) is there any problem if I take it along with food?

In fact. You probably want to take this medication with food. It's a combination of metformin and glyburide. While the metformin isn't likely going to lead to low blood sugars(hypoglycemia) even when taken without food. It's possible that the glyburide could lead to hypoglycemia if you are not eating.