Will I feel sedated if I take prazosin hydrochloride?

Possibly. First, remember that everyone is unique and respond to medications slightly differently. Some people may feel sedated with prazosin, not everyone will. It also depends on what dose you are taking and how often. Prazosin trials suggest that about 8 in 100 people feel a sedating effect. Dizziness, headache and weakness are just as common. Always tell your doctor side effects you experience.