4 doctors weighed in:
Difference between polaramine, zyrtec and claritin (loratadine)?
4 doctors weighed in

Dr. Martin Ostro
Internal Medicine - Allergy & Immunology
1 doctor agrees
In brief: All antihistamines
Polaramine is a brand of dexchlorpheniramine, a first generation sedating antihistamine similar to Chlor-Trimeton and about as effective as claritin.
Claritin, brand of Loratadine and zyrtec, brand of Cetirizine are both 2nd generation, non-sedating antihistamines. Cetirizine in head to head studies with Loratadine was found to be more effective for nasal allergies and hives.

In brief: All antihistamines
Polaramine is a brand of dexchlorpheniramine, a first generation sedating antihistamine similar to Chlor-Trimeton and about as effective as claritin.
Claritin, brand of Loratadine and zyrtec, brand of Cetirizine are both 2nd generation, non-sedating antihistamines. Cetirizine in head to head studies with Loratadine was found to be more effective for nasal allergies and hives.
Dr. Martin Ostro
Dr. Martin Ostro
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Dr. Suresh Anand
Internal Medicine - Allergy & Immunology
1 doctor agrees
In brief: Antihistamine
Benadryl, (diphenhydramine) polaramine, chlortrimeton etc.
, are old time antihistamines used for runny nose, sneezing, itching, and other allergies. They are very effective but can cause drowsiness and should be avoided in day time. Carefully read all the side effects. Zyrtec , Claritin & Allegra are newer antihistamines, with lot less drowsiness or other side effects. They work fairly well for most people.

In brief: Antihistamine
Benadryl, (diphenhydramine) polaramine, chlortrimeton etc.
, are old time antihistamines used for runny nose, sneezing, itching, and other allergies. They are very effective but can cause drowsiness and should be avoided in day time. Carefully read all the side effects. Zyrtec , Claritin & Allegra are newer antihistamines, with lot less drowsiness or other side effects. They work fairly well for most people.
Dr. Suresh Anand
Dr. Suresh Anand
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