3 doctors weighed in:

Help plz! Can skelaxin (metaxalone) be taken with hydracodone?

3 doctors weighed in
Dr. Janiece Stewart
Sports Medicine
2 doctors agree

In brief: Yes

Yes, Skelaxin (metaxalone) can be taken with hydrocodone, but they both have a side effect of sedation.
If taken together, you may feel more sluggish and sleepy than normal. I would recommend taking them at different times.

In brief: Yes

Yes, Skelaxin (metaxalone) can be taken with hydrocodone, but they both have a side effect of sedation.
If taken together, you may feel more sluggish and sleepy than normal. I would recommend taking them at different times.
Thank