6 doctors weighed in:

Should the urine tests still be performed even though the plasma free metanephrine has been done? 

6 doctors weighed in
Dr. Lea Danielsen
Family Medicine
3 doctors agree

In brief: Often no

The plasma has more sensitive and more specific and generally adequate (better) in most situations.
It would depend if the doctor is more worried about a false positive (finding pheochromcystoma you really don't have), or more worried about false negative (missing the disease when you really have it). Your doctor would decide based on your symptoms which is the bigger worry /risk.

In brief: Often no

The plasma has more sensitive and more specific and generally adequate (better) in most situations.
It would depend if the doctor is more worried about a false positive (finding pheochromcystoma you really don't have), or more worried about false negative (missing the disease when you really have it). Your doctor would decide based on your symptoms which is the bigger worry /risk.
Dr. Lea Danielsen
Dr. Lea Danielsen
Thank
1 comment
Dr. Arthur Heller
consider blood testing for chromogranin A,gastrin, and neuron specific enolase if screening for carcinoids (tumors of neuroendocrine origin). Urine tests are high when the chemicals are actively secreted; blood tests are high otherwise. Falsely elevated with PPI Rx, kidney disease.
Dr. Jean Robey
Internal Medicine - Nephrology & Dialysis

In brief: Excessive hormones

Plasma levels are points in time so often a 24 hr catches total excessive production.

In brief: Excessive hormones

Plasma levels are points in time so often a 24 hr catches total excessive production.
Dr. Jean Robey
Dr. Jean Robey
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