Can you tell me how Valtrex (valacyclovir) and abreva work with cold sores?

Abreva/ Valtrex (valacyclovir) Abreva (topical Docosanol) is an antiviral medication that can be used to treat recurrent oral/ facial herpes simplex virus infections. Valtrex (Valacyclovir) is a nucleoside analogue DNA polymerase inhibitor. Both decrease replication of the Herpes Simplex virus.