Am I supposed to take acyclovir and an antibiotic together?

Medications. Acyclovir is an anti-viral. Because of the nature by which it works, it would not affect bacteria. Antibiotics are taken for bacterial infections, and would not affect a virus. Therefore, they do not cause problems when taken together. But, each should be used according to specific indications. You need not take antibiotics just because you are taking acyclovir.