Are there any serious consequences of taking actos (pioglitazone)?

Her are some side. Effect of actos:muscle pain -- up to 5.4 percent , tooth problems -- up to 5.3 percent' , sore throat -- up to 5.1 percent , swelling or water weight gain, and others not as frequent but could serious.•symptoms of bladder cancer, symptoms of low blood sugar, trouble breathing, swelling, especially in the legs or ankles, rapid increase in weight, liver problems. Good luck.