Should I take tamoxifen to reduce the risk of a new tumor if my breast tumor does not have hormone receptors?
No. If your cancer is er negative, it will most likely not be recommended by your oncologist.
Controversial. This is a great question, probably best answered with your cancer doctor. The issue is that we don't use tamoxifen for treatment of er- breast cancers but we use it for prevention of people at high-risk; as a breast cancer survivor, you would qualify in this latter category. Even though you are more likely to develop a second ca that is er-, tamoxifen may lead to an earlier diagnosis.
Is combined tamoxifen plus hormonal therapy better for breast cancer in pre or postmenopausal women?
Need to know. Er/pr receptor status on resected tumor, as if these are negative, no role for hormone therapy. Post orpre-menopausal er+ patients are treated with the effective, cheap, low adverse effect tamoxifen, a useful drug for more than 30 years. But ovarain function precluses use of anastrazome or the newer more expensive letrozole. These all work; toxiicty and cost vary. Read more...
Estrogen supression. In general, aromatase inhibitor is only indicated for postmenopausal women ;not for premenopausal; while on the other hand, tamoxifen can be given either in pre or postmenopausal. Only thing is that tamoxifen can cause a little bit higher risk for complication -i.e. Risk for blood clots and risk for develping uterine cancer- when used in older population- age of -65 Y.O. Or above. Read more...