How are cymbalta and Effexor (venlafaxine) XR different?

Different compounds. Cymbalta and Effexor (venlafaxine) XR are different chemical compounds which are both used to treat depression and anxiety disorders; however, they share a similar "mechanism of action", in that both are serotonin and norepinephrine reuptake inhibitors (snri's). Cymbalta is also used in the management of fibromyalgia and (in europe, at least) urinary incontinence. Their side-effect profiles are also different.

Related Questions

How can snri's such as Cymbalta and Effexor (venlafaxine) control anxiety if they work on norepinephrine. Would not this increase anxiety?

Paradoxical. You would need to go to medical school to learn physiology and anatomy pathology snd psychiatry to fully understand.
Very right you are! In my practice I never use these medications, also Wellburtrin and Pristiq, (desvenlafaxine) for anxiety treatment precisely for this reason. And it's not a hypothetical concern as time after time they worsen anxiety in my humble opinion. SSRI's are much more reliable save Paxil (too short acting leading to withdrawal effects). Take care.

I have never been able to achieve an orgasm, I was on Effexor (venlafaxine) and now am on cymbalta, they are used to treat my fibromyalgia please help me!

If you were unable. To achieve orgasm prior to use of Cymbalta or Effexor (venlafaxine) - than this goes beyond medication side effect. However, sexual experience can be negatively impacted by depression, fatigue and chronic pain. May wish to explore this issue further with your physician.

I've been taking cymbalta 120mg/day for years. It's now very expensive. Is generic Effexor (venlafaxine) an alternative especially for the chronic shoulder pain?

Effexor (venlafaxine) Yes Effexor (venlafaxine) shares many of the same properties as Cymbalta and is much cheaper. Discuss with your doctor who will likely be willing to try it. You have to slowly go up icon the dosing, so don't give up too early if not helping on the starter dose. Your doctor can help you set up a dosing sequence tailor made for you.
Yes/No? Maybe. Effexor is a member of the same family as Cymbalta but it is not fda approved for the chronic pain. It could help with this but the Cymbalta appears to affect the pain sensors more than effexor. This doesnt mean it wont work. I have many pts who report benefits to the pain as well. If you are taking this for fibromyalgia- then Lyrica or savella (milnacipran) may also be of benefit.

Switching from Effexor (venlafaxine) to cymbalta reduced my drowsiness, after 2 month on cymbalta again I'm drowsy. Tapered dose from 60mg to 30mg last week. Regards?

Check MTHFR. Genotype 677 ; 1298. Almost 100% of people treated for depression for extended periods of time are positive for these genes. It is related to low folate (folic acid) ; B12 levels which causes fatigue. Getting treated can help all your meds work much better because your body will finally be able to make its own serotonin, nor-epi, ; dopamine. Tx is safer than placebo-15mg of l-methylfolate (folic acid), p5p 50mg, 4mg b12.