Few. Ace inhibitors and arbs are sexually safe for the vast majority of users. The antihypertensives with the greatest sexual side effects are thiazide diuretics and beta blockers. Clonidine (catapres) rates high as well. The drugs from the calcium blocker family are also generally sex side-effects free.
ARB's vs ACEI. Benicar (olmesartan) an arb works similarly in many ways to lisiniopril (acei). They both block at different points in the renin-angiotensin system. A by-product of the acei however is a buildup in a chemical called bradykinin, which can produce throt irritation and a dry cough in 5-10% patients. A cough like this is much less likely with an arb agent like benicar (olmesartan).
Side effect. A recent study found sprue-like enteropathy in patients taking benicar. The label has been changed to reflect this recent information. The condition mimics gluten intolerance and results and produces abdominal cramping and loose stool. This condition goes away when patients cease taking olmesartan, but can result in misdiagnosis of celiac or other GI conditions.
User dependent. Both Benicar (olmesartan) and Lisinopril are used to treat high blood pressure. Both block the effects of angiotension--a hormone that causes constriction of blood vessels and increases blood pressure. Lisinopril has been available for several years and is available as a generic (cheaper) but can cause an annoying cough. Benicar (olmesartan) is a newer drug and is more expensive. Both can cause high potassium levels.
Yes! It's unusual and rare, but agents from both the ACE inhibitor and ARB families can be taken concurrently. I've used both in cases of tough to control hypertension. When doing so it's important to get your serum potassium level checked periodically, for the two combined can result in high potassium levels in the bloodstream.
Benicar (olmesartan) Benicar (olmesartan) is an angiotensin receptor blocker and Lisinopril is an angiotensin converting enzyme inhibitor. They work in the same pathway but in different places. Their results are similar.
Dry ticklish cough. As dr. Weisberger noted, Benicar (olmesartan) is an arb while Lisinopril is an ace inhibitor. The latter has a greater risk for dry ticklish cough compared to the former. Otherwise, both are used to lower blood pressure and have been proven beneficial in heart failure as well as protecting kidneys. Cost is the other big difference b/c Benicar (olmesartan) is a brand drug while Lisinopril is a generic available for $4/mo.