4 doctors weighed in:

How does amiodarone work?

4 doctors weighed in
Dr. Michael Taylor
Critical Care
3 doctors agree

In brief: Multiple effects

Amiodarone is primarily a class iii anti-arrhythmic agent.
It prolongs the depolarization phase of cardiac muscle--the muscle takes longer to reset after contraction, slowing down the heart rate. Amiodarone also acts on sodium & potassium channels to delay conduction of the action potential through the sa & av nodes.

In brief: Multiple effects

Amiodarone is primarily a class iii anti-arrhythmic agent.
It prolongs the depolarization phase of cardiac muscle--the muscle takes longer to reset after contraction, slowing down the heart rate. Amiodarone also acts on sodium & potassium channels to delay conduction of the action potential through the sa & av nodes.
Dr. Michael Taylor
Dr. Michael Taylor
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