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What is the difference between actonel (risedronate) and fossamax?
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Dr. Arthur Heller
Internal Medicine - Gastroenterology
In brief: Similar, but differ
Both are bisphosphonate drugs, taken orally, which decrease bone breakdown by osteoclast cells, and therefore increase bone density ;#40;a marker of bone strength;#41;.
Different dosing, but can be weekly or monthly for either in osteoporosis. Were used in tumors in or to bone-now drugs mostly given IV for that. Fosamax (alendronate) stays in the system and bone longer; was thought to be more GI irritating ;#40;maybe not;#41;.

In brief: Similar, but differ
Both are bisphosphonate drugs, taken orally, which decrease bone breakdown by osteoclast cells, and therefore increase bone density ;#40;a marker of bone strength;#41;.
Different dosing, but can be weekly or monthly for either in osteoporosis. Were used in tumors in or to bone-now drugs mostly given IV for that. Fosamax (alendronate) stays in the system and bone longer; was thought to be more GI irritating ;#40;maybe not;#41;.
Dr. Arthur Heller
Dr. Arthur Heller
Thank
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