Lupus? Received positive 1:160 homogenous ANA. Familial history of lupus, breathing pain, extreme fatigue, joint pain, constant low grade fever

Cannot diagnose. This clinical history suggests a need for you to be seen by an astute clinician or even a rheumatologist. Need more info and further testing and examination before a diagnosis can be offered. What you describe can fit numerous conditions. Go soon and be evaluated. Good luck and best wishes.