High risk. for side effects, abuse and potential serious breathing problems and death. Vomiting, constipation,dizziness, drowsiness, or headache, just a few common side effects that may occur. Carefully follow your physician instructions for using fentanyl patches and remember that your doctor has prescribed this medication because he/she has thought that the benefit to you is greater than the risk.
Relatively safe. If the fentanyl patch was prescribed by your doctor he/she should have properly reviewed any contraindications. Fentanyl is an opioid medication that can cause fatigue and respiratory depression if taken in too high of a dose. 50mcg is usually a safe dose but if combined with another opioid should be used with caution. .