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What is nonsecretory myeloma?

2 doctors weighed in
Dr. Stephen Noga
Internal Medicine - Oncology
1 doctor agrees

In brief: No M-spike MM

Most myeloma cells produce an m protein or a part of it that shows up in the blood or urine.
Due to much more effective detection techniques, <5% of myelomas are non-secretory.

In brief: No M-spike MM

Most myeloma cells produce an m protein or a part of it that shows up in the blood or urine.
Due to much more effective detection techniques, <5% of myelomas are non-secretory.
Dr. Stephen Noga
Dr. Stephen Noga
Thank
Dr. Michael Thompson
Internal Medicine - Hematology & Oncology

In brief: No M-spike MM

Non-secretory multiple myeloma is myeloma that is diagnosed by the presence of plasma cells in the bone marrow and crab symptoms -- hypercalcemia, renal (kidney) problems, anemia, and bone problems (eg osteoporosis or lytic lesions) without an monoconal (m)-spike on serum protein electrophoresis (spep).
A large study by kyle et al. At mayo suggested 7% of mm pts. Likely less now with flc testing.

In brief: No M-spike MM

Non-secretory multiple myeloma is myeloma that is diagnosed by the presence of plasma cells in the bone marrow and crab symptoms -- hypercalcemia, renal (kidney) problems, anemia, and bone problems (eg osteoporosis or lytic lesions) without an monoconal (m)-spike on serum protein electrophoresis (spep).
A large study by kyle et al. At mayo suggested 7% of mm pts. Likely less now with flc testing.
Dr. Michael Thompson
Dr. Michael Thompson
Thank
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