How can tyramine cause atrial fibrillation?

Vasoactive amine. Increased tyramine can cause increases in dopamine, Epinephrine & norepinephrine (particularly when taking a type of drug called an mao-inhibitor). This can result in increased blood pressure, and it can also cause abnormal heart rhythms, including atrial fibrillation. The 1st reported case of atrial fibrillation caused by tyramine was in grimsby, england, in 1987.