My cardiolipin IgM has come back high 3 times, neutrophils slightly raised & ANA negative. Symptoms indicative of Lupus, MCTD?? Gp not worried.

See a rheumatologist. The lab tests may be unreliable especially at hospital labs. Even if negative the anticardiolipin ab may be a concern depending on your symptoms. IgM anticardiolipin Anyibody us also for many not a problem. It us best if you are having symptoms to see a specialist and get their opinion.

Related Questions

My cardiolipin IgM has come back high 3x in Nov it was 133/Jan 82/ May 102ug/l IgG is 1.1U/ml. I have symptoms indicative to MCTD. My gp not worried?

Consider aspirin. IgM anticardiolipin antibodies have an intermediate chance of causing problems. They can be a sign of autoimmune disease including MCTD. If you have had no blood clots, miscarriages or problems from this antibody it is often treated with an Aspirin a day. You should talk this over with your doctor. Read more...

I am being tested for Lupus my APTT ratio was 1.16 slightly raised and my cardiolipin IGM was 102ug/l ESR raised but ANA was normal.

Need more data . This will depend on more information that I have at this point. then ANA could be negative if only a binding essay was used rather than an immunofluorescent assay. You may fulfill criteria for lupus anticoagulant . You will need to have your physician clarify these tests which Lab did them and how accurate they are. Read more...

Can I still have lupus if my ANA and other antibodies are negative except the cardiolipin IgM and lupus coagulant! I have all the symptoms for lupus.

Yes,amongst other Dx. Anti-cardiolipin antibodies are antibodies often directed against cardiolipin & found in several diseases, including syphilis,antiphospholipid syndrome,livedoid vasculitis, vertebrobasilar insufficiency,Behçet's syndrome,idiopathic spontaneous abortion,] and systemic lupus erythematosus(SLE).They are a form of anti-mitochondrial antibody. In SLE,anti-DNA Abs &anti-cardiolipin Abs act independently. Read more...

Anti-cardiolipin IgM was checked as part of tests for mctd. It was 133 nov / 82 in jan & in feb it was 9.38. Gp says there no needs to refer or treat?

Treat and refer. I would personally put you on 81 mg of asa daily as the anticardiolipin levels can go up and down. I would also refer to a rheumatologist because your other symptoms could suggest the presence of an underlying connective tissue disorder. Read more...
? Referral. To have anti-phospholipid antibody syndrome you need to have 2 positive tests at least 3 months apart. Transient elevations are common and not risky. It's unusual that the first test was so high and it did not persist. If you still have other mctd symptoms you should see a rheumatologist. Read more...