3 doctors weighed in:
Does a monoclonal antibody reactive with the o139 antigen of e.Coli would cross react with v.Cholera o139?
3 doctors weighed in

Dr. Joseph Woods
Pathology
1 doctor agrees
In brief: Apparently not.
This does not seem likely because first that the v cholera is usually found in india and bangladesh while ecoli is usually in the U.
S., mexico, and south america. Second, the mechanisms are different because the genes for toxicity on the e coli strains are not present in the v cholera. Third, there seems to be no information on any cross reaction of these two o 139 strains.

In brief: Apparently not.
This does not seem likely because first that the v cholera is usually found in india and bangladesh while ecoli is usually in the U.
S., mexico, and south america. Second, the mechanisms are different because the genes for toxicity on the e coli strains are not present in the v cholera. Third, there seems to be no information on any cross reaction of these two o 139 strains.
Dr. Joseph Woods
Dr. Joseph Woods
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Dr. Larry Lutwick
Internal Medicine - Infectious Disease
In brief: Nope
The o (somatic) antigens of each gram-negative bacilli are numbered specifically for the organism. Therefore, the o139 antigen of v.
Cholerae is not the same as the o139 antigen of e. Coli.

In brief: Nope
The o (somatic) antigens of each gram-negative bacilli are numbered specifically for the organism. Therefore, the o139 antigen of v.
Cholerae is not the same as the o139 antigen of e. Coli.
Dr. Larry Lutwick
Dr. Larry Lutwick
Thank
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