2 doctors weighed in:
Why is fulvestrant not used with pre-menopausal patient?
2 doctors weighed in

Dr. Bryan Treacy
Gynecology
1 doctor agrees
In brief: Competition
Circulating Estradiol competes with for the estrogen receptor in premenopausal women.
Estradiol surges during ovulation to fairly high levels where in postmenopause, Estradiol is made from converting androgens/adrenal hormones (like dhea) in peripheral fat. Levels are not as high so competition for the receptor is less.

In brief: Competition
Circulating Estradiol competes with for the estrogen receptor in premenopausal women.
Estradiol surges during ovulation to fairly high levels where in postmenopause, Estradiol is made from converting androgens/adrenal hormones (like dhea) in peripheral fat. Levels are not as high so competition for the receptor is less.
Dr. Bryan Treacy
Dr. Bryan Treacy
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