9 doctors weighed in:

What causes Parkinson's disease?

9 doctors weighed in
Dr. Pavel Conovalciuc
Family Medicine
7 doctors agree

In brief: Unknown

The cause of parkinson disease is unknown.
It appears that the cause of parkinson disease leads to the depletion of Dopamine in the subtantia nigra in the brain that is responsible for the symptoms of the disease.

In brief: Unknown

The cause of parkinson disease is unknown.
It appears that the cause of parkinson disease leads to the depletion of Dopamine in the subtantia nigra in the brain that is responsible for the symptoms of the disease.
Dr. Pavel Conovalciuc
Dr. Pavel Conovalciuc
Thank
2 doctors agree

In brief: Further Detail

Polymers of a-synuclein protein form into "clumps" (intraneuronal inclusions) due to faulty "trash removal" processes in the neurons.
As a result, cellular activity is disrupted. Other problems, such as oxidative stress causing mitochondria damage (energy producing portion of cell) lead to programmed cell death, or "apoptosis." many other facets of this cascade of problems are yet to be understood.

In brief: Further Detail

Polymers of a-synuclein protein form into "clumps" (intraneuronal inclusions) due to faulty "trash removal" processes in the neurons.
As a result, cellular activity is disrupted. Other problems, such as oxidative stress causing mitochondria damage (energy producing portion of cell) lead to programmed cell death, or "apoptosis." many other facets of this cascade of problems are yet to be understood.
Dr. Robert Hutchman
Dr. Robert Hutchman
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