2 doctors weighed in:
What chromosome is affected in msud (maple syrup urine disease)?
2 doctors weighed in

Dr. Scott McLean
Clinical Genetics
1 doctor agrees
In brief: 1, 6, and 19
Msud is caused when a tightly clustered group of proteins [branched-chain ketoacid dehydrogenase] does not work properly.
This multienzyme complex has three subunits encoded by four different genes. Three of them - on chromosomes 1, 6, and 19, have been found to have mutations that can result in msud. The msud family support group (http://www.Msud-support.Org/) has more information.

In brief: 1, 6, and 19
Msud is caused when a tightly clustered group of proteins [branched-chain ketoacid dehydrogenase] does not work properly.
This multienzyme complex has three subunits encoded by four different genes. Three of them - on chromosomes 1, 6, and 19, have been found to have mutations that can result in msud. The msud family support group (http://www.Msud-support.Org/) has more information.
Dr. Scott McLean
Dr. Scott McLean
Thank
Get help from a real doctor now
Dr. Jonathan Jassey
Board Certified, Pediatrics
13 years in practice
1M people helped
Continue
107,000 doctors available
Read more answers from doctors